15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63043 | Antimalarial agent 2 | ||
Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects. | |||
T9984 | Antimalarial agent 13 | N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine | Parasite |
Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent. | |||
T22381 | Antimalarial agent 14 | 4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone | Others |
Antimalarial agent 14 (NSC-102533) is a bioactive chemical. | |||
T8767 | PfDHODH-IN-2 | Dehydrogenase , Parasite | |
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of m... | |||
T0860L | Mefloquine | Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 | Others |
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l... | |||
TN2254 | Taccalonolide A | Apoptosis , Microtubule Associated | |
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these ... | |||
TNU0295 | 2-Bromoadenosine | ||
Nucleoside Derivatives - Halo-nucleosides; 2-Modified purine nucleosides; Scaffolds and Templates; Drugs and Inhibitors; Antimalarial agent | |||
T36733 | HLI373 dihydrochloride | ||
HLI373 dihydrochloride is a potent Hdm2 inhibitor, efficiently restraining the ubiquitin ligase activity of Hdm2 and effectively prompting apoptosis in DNA-damaging agent-sensitive tumor cells[1]. Additionally, HLI373 di... | |||
T83044 | Antimalarial agent 33 | Parasite | |
Antimalarial agent 33 (compound 5g) exhibits antiplasmodial activity targeting both erythrocytic and hepatic stages of Plasmodium, with an effective concentration (EC50) of 1.1 μM against the K1 strain of P. falciparum. ... | |||
TMIH-0469 | Quinidine-d3 | ||
Quinidine-d3 is a deuterated compound of Quinidine. Quinidine has a CAS number of 56-54-2. Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal ... | |||
T73964 | Hydroxychloroquine Impurity F | ||
Hydroxychloroquine Impurity F, an impurity in Hydroxychloroquine, is identified in the synthetic antimalarial agent known for its capability to inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Additionally, Hydroxychlo... | |||
T73845 | Piperaquine tetraphosphate | ||
Piperaquine tetraphosphate, a potent antimalarial agent, demonstrates inhibitory effects against both chloroquine-sensitive and chloroquine-resistant malaria isolates. When combined with dihydroartemisinin, it holds pote... | |||
TMIH-0146 | Chloroquine-d5 | ||
Chloroquine-d5 is a deuterated compound of Chloroquine. Chloroquine has a CAS number of 54-05-7. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory ... | |||
T61058 | JMI-105 | ||
JMI-105 has the potential as an antimalarial agent. JMI-105 is a potent inhibitor of Plasmodium falciparum falcipain-2 protease (PfFP-2) that inhibits the P. falciparum strains CQ S (3D7) and CQ R (RKL-9) growth with IC ... | |||
T22242 | Amodiaquine hydrochloride | ||
Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a member of the 4-aminoquinoline class, serves as an antimalarial agent and exhibits potent oral activity as a histamine N-methyltransferase inhibitor, displaying... |